JNK phosphorylation in wild-type (WT) and glutathione S-transferase (GST) pi-isoform (GSTP)-deficient (GSTP-null) mice. Representative Western blots and densitometric analyses of the phosphorylation of JNK (p54/p46, phospho-Thr183/Tyr185) in liver (WT, n = 5; GSTP-null, n = 6; A), skeletal muscle (SKM; WT, n = 8; GSTP-null, n = 9; B), and white adipose tissue (WAT; WT, n = 8; GSTP-null, n = 10; C). P, phosphorylated; T, total. Values are means ± SE (*P < 0.05, WT vs. GSTP-null).