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. 2018 Jul 24;315(5):E892–E903. doi: 10.1152/ajpendo.00175.2018

Fig. 3.

Fig. 3.

Differentiation potential of omental adipose derived stem cells (ADSCs). Four top panels (A) show representative light micrographs obtained at day 14 of differentiation of ADSCs isolated from SUC/SIV/ART−, SUC/SIV/ART+, CBA/SIV/ART−, and CBA/SIV/ART+ macaques. Two bottom panels (A) show micrographs of boron-dipyrromethene (BODIPY) staining with and without lipid droplet accumulation. Relative expression of peroxisome proliferator-activated receptor gamma (PPARγ) (B) and early growth factor 2 (EGR-2) (C) pre- (left) and post- (right) differentiation of ADSCs isolated from SUC- (closed circles) or CBA- (closed squares) administered macaques with and without ART. There was a main effect of CBA to decrease the mRNA expression of PPARγ pre- and 14 days postdifferentiation and to decrease the mRNA expression of EGR2 at day 14 of differentiation. *P < 0.05. Data are expressed as means ± SE. n = 3 primary lines/group. ART, antiretroviral therapy; CBA, chronic binge alcohol; SIV, simian immunodeficiency virus; SUC, sucrose.