Table 2.

Tissue weights of chow- and HFD-fed PDHmKO and WT mice

	CHOW WT	CHOW PDHmKO	HFD WT	HFD PDHmKO
TA, mg	44.5 ± 3.2	44.2 ± 4.2	44.8 ± 4.0	45.9 ± 5.5
GA, mg	128.8 ± 11.4	127.8 ± 9.8	133.6 ± 8.2	131.3 ± 11.4
Liver, mg	1,358.5 ± 100.9	1,320.6 ± 111.1	1,257.1 ± 206.3	1,237.9 ± 169.6
Heart, mg	121.0 ± 12.7	120.7 ± 8.0	128.9 ± 16.1	128.6 ± 9.7
eWAT, mg	443.4 ±79.5	433.8 ± 156.5	1,977.8 ± 293.8#	2,026.6 ± 500.2#

eWAT, epididymal fat; GA, gastrocnemius; HFD, high-fat diet; PDHmKO, tamoxifen-inducible Pdha1 knockout mice; TA, tibialis anterior; WT, wild-type. Two-way ANOVA:

^#P < 0.05 main effect of diet.