Table 3.

Tissue weights of SED and EXT PDHmKO and WT mice

	SED WT	SED PDHmKO	EXT WT	EXT PDHmKO
BW, g	25.6 ± 1.6	26.1 ± 1.5	23.5 ± 0.8#	21.7 ± 1.5#
TA, mg	48.1 ± 5.6	49.3 ± 2.4	40.7 ± 3.3#	39.4 ± 4.6#
mg/g body wt	1.88 ± 0.19	1.89 ± 0.03	1.73 ± 0.11	1.81 ± 0.09
GA, mg	122.5 ± 5.9	129.4 ±8.9	110.4 ± 7.8#	107.9 ± 4.9#
mg/g body wt	4.79 ± 0.22	4.96 ± 0.21*	4.69 ± 0.23	4.97 ± 0.17*
TRI, mg	114.8 ± 4.5	115.9 ± 4.4	99.9 ± 4.2#	92.3 ± 4.3#
mg/g body wt	4.49 ± 0.18	4.45 ± 0.27	4.25 ± 0.27	4.25 ± 0.23
Heart, mg	108.7 ± 6.0	112.3 ± 9.1	117.0 ± 5.9	113.7 ± 6.1
mg/g body wt	4.25 ± 0.16	4.30 ± 0.27	5.00 ± 0.30#	5.25 ± 0.19#
eWAT, mg	474.9 ±102.8	415.2 ± 161.2	247.6 ± 67.9#	187.3 ± 13.6#
mg/g body wt	18.5 ± 3.7	15.7 ± 5.5	10.5 ± 2.7#	8.7 ± 0.7#

BW, body weight; GA, gastrocnemius; eWAT, epididymal fat; EXT, exercise-trained; PDHmKO, tamoxifen-inducible Pdha1 knockout mice; SED, sedentary; TA, tibialis anterior; TRI, triceps; WT, wild-type. Two-way ANOVA:

^#P < 0.05 main effect of diet;

^*P < 0.05 main effect of genotype.