Fig. 1.

A: patterns of weight gain across pregnancy in unrestrained mice (CON, light line; n = 20) and mice exposed to chronic restraint stress (STRESS, dark line; n = 23). B: when exposed to chronic restraint stress, pregnant female mice (dark bar) lost mass during early pregnancy (days 1 to 6) relative to pregnant unrestrained mice, which gained weight (light bar). However, during midpregnancy (after day 6), chronically stressed females gained mass at rates comparable to unrestrained females (though absolute mass is still less than unrestrained females; see 2A). ^a,b,cSignificantly different post hoc comparison (P < 0.03 for all).