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MDM2, NFκB, and Iκb protein and phosphorylation level on Day 3. Rats were injected with cisplatin (5 mg/kg) or saline, with or without MDM2 inhibitor DS‐5272 (10 mg/kg) (cisplatin (−)/DS‐5272 (−); n = 4, cisplatin (−)/DS‐5272 (+); n = 5, cisplatin (+)/DS‐5272 (−); n = 5, cisplatin (+)/DS‐5272 (+); n = 5) (A) Representative western blots and (B) densitometric analyses are shown. *P < 0.05 cisplatin (+)/DS‐5272 (−) vs cisplatin (+)/DS‐5272 (+)
