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. 2018 Nov 29;7(11):e11139. doi: 10.2196/11139

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©Susan Hewlings, Douglas S Kalman. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 29.11.2018.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Research Protocols, is properly cited. The complete bibliographic information, a link to the original publication on http://www.researchprotocols.org, as well as this copyright and license information must be included.

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Comparison between 3 subchronic doses of methylsulfonylmethane (MSM; 1 g, 3 g, and 6 g): percentage change in visual analog scale watery eyes from V1 (screening) to V3 (day 14). Significance was tested using linear mixed model analysis. *P ≤.05.