Table 2.

Brain Regions showing a Significant^a NoGo-Go Main Effect of Group Comparing Healthy Control (HC), Clinical High-Risk for Psychosis (CHR), and Early Illness for Schizophrenia (ESZ) Groups

Cluster Neuroanatomy	Omnibus Group F-map FWE Cluster- Corrected P-value	Pairwise Follow-up Testsb	Pairwise Cohen’s d	Cluster Size (in 3 mm3 Voxels)	Peak MNI Coordinates (x, y, z)
Bilateral anterior cingulate cortex BA: 9, 10, 24, 32	P = .047	HC > CHR, P < .001	HC vs CHR d = 0.98	105	6, 44, 16
3, 44, 25
HC > ESZ, P < .04	HC vs ESZ d = 0.63	−12, 44, 13
Right inferior frontal cortex (extending into insular cortex) BA: 13, 47	P = .035	HC > CHR, P < .001HC > ESZ, P = .001	HC vs CHR d = 0.84HC vs ESZ d = 0.96	95	36, 23, −1124, 23, −1136, 14, −14

^aCluster-corrected P-values are family-wise error (FWE) corrected, at a height threshold of P < .005; extent = 20 voxels. Brodmann area = BA.

^bTukey–Kramer HSD post hoc tests, 2-tailed, P < .05.