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. 2018 Dec 7;8:592. doi: 10.3389/fonc.2018.00592

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Copyright © 2018 Kalamegam, Sait, Ahmed, Kadam, Pushparaj, Anfinan, Rasool, Jamal, Abu-Elmagd and Al-Qahtani.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative phase contrast images of the tumor spheres (TS) of (A) OVCAR3 treated with hWJSC-CM; (B) TS of OVCAR3 treated with hWJSC-CL; (C) TS of SKOV3 treated with hWJSC-CM and (D) TS of SKOV3 treated with hWJSC-CL. Decrease in TS size, numbers and cell death/degeneration (indicated by thin black arrows) were more evident following treatment with hWJSC-CL (10, 15, and 30 μg/ml) than with hWJSC-CM (50, 75, and 100%) for 48 h.