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The comparison of serum CTX (bone resorption biomarker) levels
| Genotype |
One-Way ANOVA |
||||
|---|---|---|---|---|---|
| Control (n = 25) | PT-PTH1R−/− (n = 14) | PT-PTH1R/KL−/− (n = 13) | F | P value | |
| CTX, ng/ml | 30.94 ± 2.26 | 31.48 ± 2.18 | 45.66 ± 2.34a,b | 10.1 | 0.0002 |
Data represent the means ± SD. Serum CTX was measured by ELISA in Control mice, PT-PTH1R−/− mice, and PT-PTH1R/KL−/− mice at 9 wk of age. CTX, cross-linked C telopeptide.
P < 0.001, Control vs. PT-PTH1R/KL−/−,
P < 0.01, PT-PTH1R−/− vs. PT-PTH1R/KL−/−.
