Fig. 2.

Functional bladder analyses in cystometry. Representative cystometrogram traces from unanesthetized, unrestrained control (A) and NMS (B) mice during a continuous intravesical infusion (10 μl/min) of room-temperature saline. Data from male and female mice are shown on the left and right, respectively. Volume infused (VI, top), voided volume (VV, middle), and bladder pressure (BP, bottom) are shown. *In voided volume traces (middle) show intermittent voids. Arrowheads in the bladder pressure traces (bottom) indicate examples of nonvoiding bladder contractions. NMS, neonatal maternal separation.