Table 2.
Comparison of urodynamic parameters in each group
| Infused, µl | Void, µl | Pves max, mmHg | Nonvoid contractions | |
|---|---|---|---|---|
| Control | 151 ± 10 | 142 ± 8 | 16.5 ± 0.9 | 0.7 ± 0.1 |
| NMS | 106 ± 10** | 98 ± 9† | 15.1 ± 0.5 | 2.9 ± 0.4† |
| Male | Infused, µl | Void, µl | Pves max, mmHg | Nonvoid contractions |
|---|---|---|---|---|
| Control | 164 ± 16 | 162 ± 10 | 18.3 ± 0.8 | 0.4 ± 0.1 |
| NMS | 121 ± 16 | 112 ± 15** | 16.9 ± 0.6 | 2.5 ± 0.5† |
| Female | Infused, µl | Void, µl | Pves max, mmHg | Nonvoid contractions |
|---|---|---|---|---|
| Control | 136 ± 11 | 118 ± 9 | 14.3 ± 1.5 | 1.1 ± 0.3 |
| NMS | 90 ± 8** | 81 ± 9** | 13.1 ± 0.7 | 3.3 ± 0.5† |
Means ± SE. NMS mice showed a significant decrease in bladder capacity, voided volume, and a significant increase in the number of nonvoid contractions compared with those in the control group (N = 10–11 per each group). Both male and female mice showed the same patterns of urodynamic changes in NMS mice (N = 5–6 per each group). NMS, neonatal maternal separation; Pves max, maximum intravesical pressure at micturition.
**
P < 0.01;
†
P < 0.001 vs. control mice.