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. 2018 Aug 15;315(5):F1358–F1369. doi: 10.1152/ajprenal.00249.2018

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Fig. 8. — Indicators of renal dysfunction. Plasma concentrations of urea (A) and creatinine (B) and the urinary albumin-to-creatinine ratio (C) are shown for rats 24 h and 5 days after sham ischemia (○) or bilateral renal ischemia (●); n = 6 per group. Values are expressed as medians (25th percentile, 75th percentile). Comparisons were performed using the Mann-Whitney U-test. Because comparisons were made at two time points, P values were conservatively adjusted using the Dunn-Sidak method with k = 2. P_Tr, P_T, and P_Tr*T are the outcomes of two-way analysis of variance on ranking with the factors treatment (Tr) and time (T).