Table 3.
The regions of decreased gray matter volume in AN patients compared with HC identified by the main meta-analyses
| Region | Maximum | Cluster | Jackknife sensitivity analysis | |||
|---|---|---|---|---|---|---|
| MNI coordinates x, y, z | SDM z-score | p-Value uncorrected | Number of voxels | Breakdown (no. of voxels) | ||
| L median cingulate | −4, −30, 44 | −3.223 | ~0 | 2348 | L median cingulate (849) R median cingulate (363) L precuneus (347) R precuneus (269) L supplementary motor area (250) L posterior cingulate gyrus (138) R supplementary motor area (82) R posterior cingulate gyrus (50) |
21 of 21 |
| L cerebellum | −28, −54, −32 | −2.137 | 0.001114726 | 181 | L cerebellum, hemispheric lobule VI, BA 37 (96) L cerebellum, hemispheric lobule VI (59) L cerebellum, hemispheric lobule VI, BA 19 (18) L cerebellum, crus I (8) |
18 of 21 (Amianto et al.; D’Agata et al.; Fonville et al.) |
| R cerebellum, crus I | 30, −50, −22 | −2.011 | 0.001207650 | 85 | R cerebellum, crus I (42) R cerebellum, hemispheric lobule VI (43) |
19 of 21 (Fonville et al.; Phillipou et al.) |
The jackknife sensitivity analysis column gives the number of studies whose omission does not affect the finding, and abbreviated reference citations for the remainder which do
BA Brodmann area, GM gray matter, MNI Montreal Neurological Institute Space, L left, R right, SDM seed-based d mapping