Table 2.
Baseline comparison between multiple sclerosis (MS) patients and healthy controls.
| Task | Outcome | Mean difference (MS vs non-MS) | Lower CI | Upper CI | p-Value | Effect size | |
|---|---|---|---|---|---|---|---|
| PASAT | Correct | 9.45 | 5.81 | 13.08 | <0.0001 | –0.97 | |
| CBB | |||||||
| Detectiona | Accuracy | 0.037 | –0.003 | 0.077 | 0.07 | 0.36 | |
| Speed | –0.066 | –0.100 | –0.031 | 0.0003 | –0.67 | ||
| Identificationa | Accuracy | 0.007 | –0.069 | 0.082 | 0.86 | 0.035 | |
| Speed | –0.062 | –0.097 | –0.026 | 0.0009 | –0.698 | ||
| One card backa | Accuracy | 0.08 | 0.001 | 0.151 | 0.047 | 0.409 | |
| Speed | –0.08 | –0.118 | –0.038 | 0.0002 | 0.79 | ||
| One card learninga | Accuracy | 0.061 | 0.017 | 0.104 | 0.00063 | 0.568 | |
| Speed | –0.06 | –0.103 | –0.017 | 0.007 | –0.56 | ||
| Groton Maze learning | Errors | –10.72 | –16.74 | –4.70 | 0.0006 | –0.72 | |
| Continuous paired associate learning | Errors | –17.04 | –27.23 | –6.86 | 0.00013 | –0.68 | |
CBB: CogState Brief Battery; CI: confidence interval; PASAT: Paced Auditory Serial Addition Test.
Lower values correspond to a slower reaction time or decreased accuracy.
aValues shown after base 10 logarithmic transformation.