Table 4.

Differences in sensation and balance measures between breast cancer survivors with and without paclitaxel-induced peripheral neuropathy.

Characteristic	No neuropathy	Neuropathy	Statistic; p value
	50.0% (n = 25)	50.0% (n = 25)
	Mean (SD)	Mean (SD)
Sensation measuresa
Light touch—lower extremity sites (out of nine)b	0.1 (0.3)	1.5 (1.5)	t = −4.42, p <.001
Cold—lower extremity sites out of fourc	1.5 (1.3)	2.3 (1.0)	t = −2.54, p = .014
Pain—lower extremity sites (out of nine)d	1.6 (1.6)	3.0 (2.1)	t = −2.71, p = .009
Vibration—lower extremity sites (volts)e	16.2 (8.1)	25.1 (14.0)	t = −2.76, p = .009
Balance measures
Trouble with balance (% yes (n))f	13.0 (3)	76.0 (19)	FE, p <.001
Severity of balance trouble (0–10)g	1.7 (1.2)	5.6 (2.9)	t = −4.16, p = .004
Frequency of balance trouble (0–10)h	2.3 (1.5)	5.1 (3.2)	t = −2.37, p = .060
Distress from balance trouble (0–10)i	1.7 (1.2)	5.8 (3.2)	t = −4.17, p = .003
Timed get up and go test (>13.5 s = higher risk for falls)	6.1 (1.1)	8.6 (3.1)	t = −3.76, p = .001
Fullerton Advanced Balance test (≤25 is associated with a higher risk of falls)	38.0 (3.1)	33.4 (6.7)	t = 3.14, p = .004

Note: FE: Fisher’s exact test; SD: standard deviation.

^aChanges in sensation are reported for the dominant extremity.

^bLower extremity sites for light touch were as follows: pad of great toe, pad of third toe, pad of fifth toe, base of heel, metocarpophalangeal (MP) joint of great toe, MP joint of third toe, MP joint of fifth toe, midway along tibia, and patella.

^cLower extremity sites for cold were as follows: top of great toe at first MP joint, pad of great toe, dorsum of foot midpoint, and medial malleolus.

^dLower extremity sites for pain were as follows: pad of great toe, pad of third toe, pad of fifth toe, base of heel, MP joint of great toe, MP joint of third toe, MP joint of fifth toe, midway along tibia, and patella.

^eLower extremity sites for vibration were as follows: dorsal IP joint of great toe, medial malleolus, and patella.

^fSince your chemotherapy, have you had trouble with your balance?

^gAt its worst, how severe is the trouble with your balance (0 = not at all severe to 10 = extremely severe)?.

^hHow often do you have trouble with your balance (0 = never to 10 = always)?

ⁱAt its worst, how distressing is the trouble with your balance (0 = not at all distressing to 10 = extremely distressing)?