Table 5.
Differentially expressed mitochondrial dysfunction-related genes between breast cancer survivors with and without paclitaxel-induced peripheral neuropathy (PIPN).
| Ensemble gene ID | Gene symbol | Name | Entrez ID | logFCa | Adjusted p valueb |
|---|---|---|---|---|---|
| ENSG00000126432 | PRDX5 | Peroxiredoxin 5 | 25824 | −0.987 | .0098 |
| ENSG00000182512 | GLRX5 | Glutaredoxin 5 | 51218 | −1.703 | .0062 |
| ENSG00000214253 | FIS1 | Fission, mitochondrial 1 | 51024 | −1.062 | .0062 |
| ENSG00000170315 | UBB | Ubiquitin B | 7314 | −1.374 | .0062 |
alogFC: Fold change of the log2 transformed normalized gene expression counts between the groups. A negative logFC denotes lower expression in survivors with PIPN as compared to those without PIPN.
bp Value adjusted using the Benjamini–Hochberg method.