Table 6.
Significantly perturbed mitochondrial dysfunction-related Kyoto Encyclopedia of Genes and Genomes pathways between breast cancer survivors with and without paclitaxel-induced peripheral neuropathy.
| Pathway ID | Pathway name | Total perturbation | Adjusted pPerta |
|---|---|---|---|
| hsa04137 | Mitophagy–animal | 11.79 | .004 |
| hsa04150 | mTOR signaling pathway | 9.60 | .004 |
| hsa04152 | AMPK signaling pathway | 8.99 | .004 |
| hsa04151 | PI3K-AKT signaling pathway | 8.04 | .004 |
| hsa04066 | HIF-1 signaling pathway | 7.45 | .004 |
| hsa04216 | Ferroptosis | 6.98 | .004 |
| hsa04115 | p53 signaling pathway | 5.68 | .007 |
| hsa04146 | Peroxisome | 5.32 | .007 |
| hsa04068 | FoxO signaling pathway | 5.32 | .008 |
| hsa04218 | Cellular senescence | 5.36 | .008 |
apPert: Perturbation p value adjusted using the Benjamini–Hochberg method.