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. 2018 Dec 12;6(12):2325967118813083. doi: 10.1177/2325967118813083

TABLE 1.

Summary of Injury-Specific NFL Combine Level 3 Retrospective Studiesa

First Author Injury/Surgery Years Injuries (Athletes), n Methods Results
Cervical spine
 Schroeder35 Cervical spine diagnosis 2003-2011 143 (143) Study on athletes with a history of a cervical spine diagnosis
Control group matched by age, position, year drafted, and round drafted
Outcomes: draft status, years played, games played and started, performance
Most common diagnoses: spondylosis, stenosis, cervical sprain/strain
Athletes with cervical spine diagnosis were less likely to be drafted vs controls (P = .001)
Athletes drafted who had a cervical spine diagnosis had decreased total games played (P = .01) but no significant differences in number of games started or performance score vs controls
Athletes with cervical spine stenosis and those with prior cervical spine surgery demonstrated no difference in performance-based outcomes and no reports of neurological injury during their careers
 Presciutti30 Chronic stinger syndrome 2005-2006 28 (28) Study on athletes with cervical spine MRI
Athletes with chronic stingers vs those without chronic stingers and age-matched nonathletes
Outcomes: mean subaxial cervical space available for the cord (MSCSAC), mean subaxial cervical Torg ratio
Athletes with chronic stingers had lower MSCSAC (4.5) vs those without chronic stingers (5.8; P < .01) and controls (6.7; P < .001)
A critical value of 5.0 mm for the MSCSAC produced a sensitivity of 80% and a negative likelihood ratio of 0.23 for predicting chronic stingers
MSCSAC more accurate than the classic Torg ratio
Foot
 Carreira7 Jones fracture/fifth metatarsal diaphyseal stress fracture 2004-2009 74 (68) Study on athletes with a history of a Jones or proximal diaphyseal fifth metatarsal fracture
Control group matched by draft status, player position, BMI, and medical grade
Outcomes: games played and started, years played
Among all fractures, 61% were Jones, 20% were proximal diaphyseal, and 19% were of indeterminate location
No significant differences in mean games played/started, total years, and likelihood of being drafted between fracture and control groups
 Tu37 Jones fracture fixation 2012-2015 41 (40) Study on athletes who had undergone fixation of Jones fracture
Control group with no history of Jones fracture fixation
Outcomes: draft status, games played and started
All fractures treated with intramedullary screw fixation with 92% complete union
No athletes, including those with incomplete union, had any limitations in strength of ROM
No significant differences between percentage drafted, games played, or games started between fracture and control groups
 McHale25 Lisfranc injury 2009-2015 41 (41) Study on athletes with a history of a Lisfranc injury
Control group with no history of midfoot injury matched by position
Outcomes: draft status and position, games played and started, NFL career length ≥2 y
63% of injuries treated operatively
Athletes treated surgically were more likely to go undrafted (P = .04) and had a worse draft position (P = .03) vs those treated nonoperatively
Athletes with Lisfranc injury had worse draft position (P = .04) and fewer games played (P = .001) and started (P = .08) vs controls
Athletes with >2-mm residual displacement on radiograph had worse outcomes across all measurements vs those with ≤2-mm displacement
 Vopat38 Navicular injury 2009-2015 15 (14) Study on athletes with a history of a navicular injury
Control group matched by position and composed of players who missed <2 games in college and did not undergo previous surgery or have a documented injury
Outcomes: draft status and position, games played and started, NFL career length ≥2 y
11 overt navicular fractures, 3 stress reactions on MRI
8 athletes with navicular fracture underwent surgery
Evidence of ipsilateral talonavicular arthritis in 75% of those with fracture vs 60% in the uninjured foot (P = .04)
57% of athletes with navicular injury were undrafted vs 31% of the control group (P = .001)
29% of athletes with navicular injury played ≥2 y vs 70% of the control group (P = .02)
Hip/groin
 Knapik14 Athletic pubalgia repair 2012-2015 55 (55) Study on athletes who had undergone surgical repair for athletic pubalgia
Control group without history of athletic pubalgia repair
Outcomes: draft status, current NFL status, games played and started, positive pathology (pubic plate injury, rectus abdominis injury, adductor aponeurosis injury, or combination thereof) on postsurgical MRI
No significant differences in games played/started, draft status, or current status between athletic pubalgia and control groups
53% of those with postsurgical MRI showed positive pelvic pathology
No significant differences in games played/started, draft status, and current status between athletes with negative and positive MRI pathologies
Offensive linemen (P = .005) and athletes who had surgery <1 y before NFL Combine (P = .03) were more likely to have positive pathology on MRI
 Knapik17 Hip arthroscopic surgery 2012-2015 15 (14) Study on athletes who had undergone hip arthroscopic surgery
Control group with no history of hip arthroscopic surgery
Outcomes: draft status, games played and started, current status
Acetabular labral tearing was treated with repair alone (73%), debridement alone (7%), or repair and debridement (13%) in 93% of hips undergoing arthroscopic surgery
Decompression for FAI was performed in 33% of hips
No significant differences in draft status, current status, games played, or games started between surgical and control groups
Knee
 Keller13 ACLR 2010-2014 NA (98) Study on athletes with a history of ACLR
Control group matched by age, size, and position
Outcomes: 40-yd dash, vertical leap, broad jump, shuttle drill, 3-cone drill
No significant differences in 40-yd dash times, vertical leap, broad jump, shuttle drill times, and 3-cone drill times between ACLR and control groups
 Provencher31 ACLR 2009-2015 NA (110) Study on athletes with a history of ACLR
Injury-free control group matched by position and draft class
Outcomes: draft status, games played and started, snap percentage
Athletes with prior ACLR were drafted lower (P = .019), played and started fewer games (P ≤ .003), and had lower snap percentage (P < .001)
Defensive linemen, defensive backs, and linebackers were most affected positions
 Provencher32 Chondral injury 2009-2015 124 (101) Study on athletes with knee chondral injuries without history of prior knee surgery
Injury-free drafted control group
Outcomes: draft position, games played and started, snap percentage, position-specific performance metrics
Patella (63%) and trochlea (34%) were most commonly affected
Defensive linemen at highest risk for unrecognized injuries (P = .015)
Athletes with untreated chondral injuries had lower draft position, played fewer games, and started fewer games than controls (P < .001)
Subchondral bone edema and full-thickness cartilage injuries were associated with fewer games played (P = .003)
 Chahla8 Meniscectomy and chondral injury 2009-2015 249 (247) Study on athletes with chondral injury in the setting of prior meniscectomy
Compared with injury-free control group matched by position
Condition of the meniscus graded with modified ISAKOS scores
Condition of the cartilage graded with ICRS scores
Outcomes: draft position, games played and started, snap percentage
287 players had a prior meniscectomy (206 lateral, 81 medial)
Poorer meniscal score was associated with worse chondral pathology, especially in the lateral compartment
Controls had greater number of games played and started and higher snap percentage vs those with prior meniscectomy of at least 10% volume
Athletes with severe chondral lesions (ICRS grade 4) had significantly worse performance metrics vs controls
 Logan22 MCL injury 2009-2015 337 (301) Study on athletes with a history of MCL injury
Injury-free control group
Outcomes: draft position, games played and started, snap percentage
55% had additional soft tissue injury (eg, meniscus, ACL, PCL)
No significant differences in draft status/position, games played, or games started between athletes with MCL injury and controls
Athletes with isolated MCL injury had better draft position (P = .034), proportion playing ≥2 NFL seasons (P = .022), games played (P = .014), and games started (P = .020) vs athletes with combined injuries
 Chahla9 Posterolateral corner injury 2009-2015 23 (23) Study on athletes with a history of posterolateral corner injury
Inclusion criteria: positive clinical findings or previous surgery consistent with a posterolateral corner injury
Compared with surgery-free control group matched by position
Outcomes: varus stress physical examination, draft status, games played and started
70% of injuries treated surgically, 30% were diagnosed on clinical examination
57% were combined injuries (with ACL, MCL, or PCL), all treated surgically
87% of injuries treated surgically were stable on examination, whereas none of the injuries managed nonoperatively were stable
No significant differences in draft status, games played, or games started between posterolateral corner injury and control groups; athletes with surgically managed posterolateral corner injuries started fewer games than controls (P = .03)
Lumbar spine
 Moorman27 Hyperconcavity of the lumbar vertebral end plates 1992-1993 88 (88) Study on linemen with radiographic evidence of hyperconcavity of lumbar vertebral end plates
Control group of nonathletes matched by age
Outcomes: incidence, association with lumbosacral spine symptoms
Hyperconcavity present in 33% of linemen vs 8% in controls (P < .0001)
Trend toward lower incidence of lumbosacral spine symptoms for those with hyperconcavity (P = .1839)
When hyperconcavity was present, all 5 lumbosacral disk spaces were commonly affected
 Paxton29 Hyperconcavity of the lumbar vertebral end plates 1992-1993 93 (93) Study on linemen with radiographic evidence of hyperconcavity of the lumbar vertebral end plates
Control group matched by year and round drafted, surgery and injury history
Outcomes: percentage who played at least 1 NFL game, career length, games played and started
No difference in likelihood of playing in NFL, years played, games played, or games started between athletes with lumbar spine hyperconcavity and controls
No association between lumbar spine hyperconcavity and BMI
 Schroeder34 Lumbar spine diagnosis 2003-2011 414 (414) Study on athletes with a history of a lumbar spine diagnosis
Control group matched by age, position, year and round drafted
Outcomes: draft status, years played, games played and started, performance
Most common diagnoses: degenerative spondylosis, herniated disc, spondylolysis with/without spondylolisthesis, strain
Athletes without lumbar spine diagnosis were more likely to be drafted than those with a diagnosis (P < .001)
Drafted athletes with preexisting lumbar spine injuries had decreased number of years played (P = .001), games played (P = .0001), and games started (P = .02) but not performance score (P = .013) vs controls
Spondylolysis was associated with decreased career longevity (P < .05)
Shoulder
 Knapik16 Bristow/Latarjet procedure 2012-2015 10 (10) Study on athletes who had undergone Bristow or Latarjet surgery
Control group with history of isolated shoulder soft tissue repair without bony augmentation or fracture fixation
Outcomes: draft status, games played and started, status after the athletes’ first NFL season
70% had deficits in shoulder motion; 40% had evidence of mild glenohumeral arthritis
40% of athletes were drafted into NFL
No significant risk of diminished participation with regard to games played and started vs controls
60% remained on active NFL roster after their first season
 Knapik15 Labral repair 2012-2015 146 (132) Study on athletes with a history of labral repair and MRI of the operative shoulder
Control group with no history of labral repair
Outcomes: association between primary labral repair location and presence and location of recurrent tearing, concomitant shoulder pathology, arthritis, draft status, games played and started
32% of shoulders had recurrent labral tears on MRI
Athletes with recurrent tears were more likely to have undergone bilateral labral repairs (P = .048) and possess concomitant shoulder pathology (P < .001)
Recurrent labral tearing was more common in posterior labrum in the setting of prior posterior labral repair (P = .032)
No significant differences in games played and games started between athletes who had undergone labral repair and controls
No significant differences in chance of being drafted, games played, and games started between athletes with recurrent tearing and intact repairs
 Murphy28 Anterior labral injury 2009-2015 226 (206) Study on athletes with a history of an anterior labral injury
Control group without history of surgery and >2 games missed in college
Outcomes: draft status, games played and started, snap percentage
72% had surgical intervention, 38% were treated nonoperatively
No significant differences in draft status, games played, games started, or snap percentage vs controls
Concomitant injury (eg, SLAP tear, glenoid bone loss, Hill-Sachs lesion) was associated with lower draft position (P = .003)
 Gibbs11 Rotator cuff tear 2003-2011 NA (49) Study on athletes with a history of a rotator cuff tear
Control group matched by age, position, year and round drafted
Outcomes: draft status, years played, games played and started, performance score
45% underwent surgical intervention, 55% treated nonoperatively
Athletes with rotator cuff tear were less likely to be drafted vs controls (P = .002)
Athletes who were drafted started fewer games (P = .02) and played fewer years (P = .04) and fewer games (P = .04) vs controls
 Chambers10 SLAP tears 2003-2011 NA (25) Study on athletes reporting a history of a SLAP tear
Control group with no documented shoulder pathology matched by position, age, and draft year and round
Outcomes: draft success, games played and started
SLAP repairs most performed in offensive linemen (32%)
Drafted athletes with SLAP tears played fewer games (P = .049) and had fewer game starts (P = .036) vs controls

aACL, anterior cruciate ligament; ACLR, ACL reconstruction; BMI, body mass index; FAI, femoroacetabular impingement; ICRS, International Cartilage Repair Society; ISAKOS, International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine; MCL, medial collateral ligament; MRI, magnetic resonance imaging; NA, not available; NFL, National Football League; PCL, posterior cruciate ligament; ROM, range of motion; SLAP, superior labrum anterior-posterior.