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Exposure-adjusted rates of sCr elevations and resolution of sCR elevations
Exposure-adjusted rates of serum creatinine 1.5 × baseline (A) and 2.0 × baseline (C) and resolution of the elevations (B & D, respectively) in the core and core + extension studies. LESU200/400: lesinurad 200 mg/400 mg; PY: person-years; sCr: serum creatinine; XOI: xanthine oxidase inhibitor.
