Table 5.

Factors that moderate the correlations of anxiety and depression between adults with cancer and their family caregivers

Factors	5a: AC-related variables					5b: FC-related variables
	nc	Correlation of Anx		Correlation of Dep		nc	Correlation of Anx		Correlation of Dep
		r	P-value	r	P-value		r	P-value	r	P-value
Age (years)
< 30	21	0.391	0.089	0.525a	0.017	83	0.414 b	<0.001	0.354b	0.001
30 ~  45	127	0.156	0.082	0.122	0.174	217	0.320 b	<0.001	0.282b	< 0.001
46 ~  60	247	0.424b	< 0.001	0.358b	< 0.001	203	0.327 b	< 0.001	0.309b	< 0.001
> 60	218	0.312b	< 0.001	0.335b	< 0.001	103	0.308b	0.002	0.363b	< 0.001
Gender
Male	309	0.373b	< 0.001	0.330b	< 0.001	302	0.274b	< 0.001	0.284b	< 0.001
Female	310	0.269b	< 0.001	0.289b	< 0.001	320	0.352b	< 0.001	0.319b	< 0.001
Marital status
Married	570	0.323b	< 0.001	0.312b	< 0.001	555	0.303b	< 0.001	0.290b	< 0.001
Not married	53	0.225	0.117	0.238	0.086	67	0.486b	< 0.001	0.513b	< 0.001
FCs’ relationship with patients
Spouses						334	0.330b	< 0.001	0.360b	< 0.001
Offspring						209	0.387b	< 0.001	0.335b	< 0.001
Parents						20	0.425	0.070	0.454a	0.044
Sibling						39	0.028	0.862	−0.128	0.438
Others						21	0.013	0.954	−0.025	0.916
Education levels
Primary school or less	346	0.269b	< 0.001	0.231b	< 0.001	246	0.263b	<0.001	0.202b	0.001
High school	194	0.376b	<0.001	0.427b	<0.001	217	0.339b	<0.001	0.348b	<0.001
University or above	81	0.308b	0.006	0.280a	0.011	156	0.335b	<0.001	0.355b	<0.001
Working status
Working	360	0.297b	<0.001	0.307b	<0.001	400	0.268b	<0.001	0.264b	<0.001
Not working	259	0.322b	<0.001	0.280b	<0.001	220	0.385b	<0.001	0.353b	<0.001
Duration in their role as a family caregiver
< 6 months						340	0.228b	<0.001	0.189b	<0.001
6 months~ 2 years						186	0.505b	<0.001	0.528b	<0.001
> 2 ~ 5 years						52	0.257	0.066	0.300a	0.029
> 5 years						37	0.105	0.538	0.255	0.128
Informed about the disease
Ill-informed	256	0.276b	<0.001	0.233b	<0.001	151	0.303b	<0.001	0.162a	0.046
Partly informed	248	0.361b	<0.001	0.360b	<0.001	273	0.319b	<0.001	0.332b	<0.001
Well-informed	115	0.149	0.112	0.173	0.065	198	0.310b	<0.001	0.351b	<0.001
Time spent by family caregivers in caring for patients / day
< 2 h						54	0.361b	0.007	0.234	0.085
2~4 h						85	0.344a	0.001	0.391b	<0.001
> 4~6 h						72	0.400b	<0.001	0.361b	0.002
> 6~8 h						84	0.405b	<0.001	0.425b	<0.001
> 8 h						322	0.242b	<0.001	0.217b	<0.001
Type of cancer
Breast cancer	67	0.376b	0.002	0.351b	0.003
Ovarian and cervical cancer	88	0.176	0.101	0.157	0.135
Esophageal and gastric cancer	147	0.551b	<0.001	0.485b	<0.001
Colorectal cancer	83	0.306b	0.005	0.228a	0.038
Liver cancer	59	0.110	0.410	0.168	0.203
Lung cancer	85	0.203	0.062	0.295b	0.007
Others	74	0.342b	<0.001	0.306b	0.008
Type of treatment
Chemotherapy	267	0.330b	<0.001	0.305b	<0.001
Chemotherapy +surgery	112	0.250b	0.009	0.202a	0.035
Chemotherapy +radiotherapy	160	0.380b	<0.001	0.361b	<0.001
Chemotherapy+ others	80	0.207	0.067	0.270a	0.015
5c: Family-related variables
Relationship with their family members pre-cancer
Very good	459	0.321b	<0.001	0.326b	<0.001
Normal	157	0.252b	0.001	0.172a	0.032
Poor	8	0.219	0.602	−0.156	0.712
Relationship with family members changed post-cancer
Improving	213	0.345b	<0.001	0.390b	<0.001
No change	377	0.293b	<0.001	0.250b	<0.001
Worsening	31	0.312	0.088	0.246	0.183
Financial burden on the family due to cancer treatment
Serious	400	0.316b	<0.001	0.346b	<0.001
Moderate	187	0.232b	0.002	0.154a	0.035
Mild or None	33	0.613b	<0.001	0.380a	0.029

Note: AC Adults with Cancer, FC Family Caregivers, Anx Anxiety, Dep Depression, Correlation of Anx Correlation of Anx between adults with cancer and their family caregivers, Correlation of Dep Correlation of Dep between adults with cancer and their family caregivers

^aCorrelation is significant at the 0.05 level (2-tailed)

^bCorrelation is significant at the 0.01 level (2-tailed)

^cThe total n does not equal 641 because of missing values