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. 2018 Dec 10;13:8395–8410. doi: 10.2147/IJN.S188016

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© 2018 Shobaki et al. This work is published and licensed by Dove Medical Press Limited

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The YSK05/12-LNP fluorescence intensity under different pH values measured by TNS assay.

Notes: The pKa value of the LNP membranes was determined to be the pH value with 50% of maximal fluorescence intensity. Data represent the mean (n=3).

Abbreviations: LNP, lipid nanoparticle; pKa, acid dissociation constant; TNS, 6-(p-toluidino)-2-naphthalenesulfonic acid.