Skip to main content
. Author manuscript; available in PMC: 2020 Jan 15.
Published in final edited form as: Coord Chem Rev. 2017 Sep 22;379:99–120. doi: 10.1016/j.ccr.2017.09.002

Figure 13.

Figure 13

Self-assembled multifunctional nanoporphyrin. A) Schematic illustration of a multifunctional NP self-assembled by a representative porphyrin–telodendrimer, PEG5k-Por4-CA4, composed of four pyropheophorbide-a molecules and four cholic acids attached to the terminal end of a linear PEG chain. B) PET image of nude mice bearing SKOV3 ovarian cancer xenografts at 4, 8, 16, 24 and 48 h post injection of 64Cu-labelled NPs (150–200 ml, 64Cu dose: 0.6–0.8 mCi). The white arrow points to the tumor site. C) PET-MR images of tumor slices of nude mice bearing A549 lung cancer xenograft at 4 or 24 h post injection of dual-labelled NPs. White arrow points to the necrotic area in the center of the tumor. Permission obtained from Ref.[118]. Copyright (2014) by Springer Nature.