Examples of natural metalloporphyrins. A) Heme B, an iron(II)-porphyrin compound in red blood cells, participates in the transportation of oxygen. B) ChlorophyII a, a magnesium chlorin, plays crucial role in the photosynthesis. C) Methylcobalamin (vitamin B12), a vitamin required for nervous system function. D) Cofactor F430 catalyzes methanogenesis in methanogenic archaea.