Figure 25.
Oxygen responsive Pt-porphyrin probes. A) The chemical structure of PtPFPP. B) The (Left) SEM and (Right) AFM images of the PtPFPP-RL100 NPs. C) Phosphorescence lifetime (τ) calibrations for three probes obtained with non-respiring MEF cells. ER9Q-PtCP, MitoXpress and Nano2 were design for monitoring the pericellular (PC), extracellular (EC), and intracellular (IC) O2 concentrations, respectively. Permission obtained from Ref.[186]. Copyright (2012) by American Chemical Society.