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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Pediatr Nephrol. 2018 Aug 29;34(1):117–128. doi: 10.1007/s00467-018-4049-5

Table 3.

Baseline laboratory measures by lupus nephritis damage status in the cohort (N = 89)

Measure NGAL Ceruloplasmin KIM-1 MCP-1 Osteopontin TGFB Adiponectin Transferrin VDBP LFABP* UPCR
Correlations of unadjusted urine concentrations
NGAL 1.00
CP 0.29** 1.00
KIM-1 0.50**** 0.25** 1.00
MCP-1 0 53**** 0.50**** 0.62**** 1.00
Osteopontin −0.13 0.21 0.13 0.25** 1.00
TGFB 0.53**** 0.42*** 0.50**** 0.50**** 0.22 1.00
Adiponectin 0 43*** 0.55**** 0.41*** 0.45**** 0.20 0.49**** 1.00
Transferrin 0 40*** 0.48**** 0.52**** 0.55**** 0.15 0.42*** 0.45****
VDBP 0.56**** 0.44*** 0.50**** 0 47**** 0.02 0.52**** 0.64**** 0.60**** 1.00
LFABP 0.58**** 0.22 0.58**** 0.62**** 0.23 0.45**** 0.45**** 0.60**** 0.74**** 1.00
UPCR 0.30** 0.31** 0.30** 0.17 0.00 0.27** 0.45**** 0.39*** 0.48**** 0.48**** 1.00
GFR −0.34*** −0.14 −0.38*** −0.31** 0.23** −0.16 −0.17 −0.19 −0.23** −0.39**** −0.20
NIH-C1 0.16 −0.08 0.08 −0.04 −0.35*** −0.06 0.06 −0.07 0.06 −0.09 0.18
Correlations after urine albumin adjustment
UPCR 0.03 −0.19 −0.23*** −0.27*** −0.22*** 0.06 0.25*** 0.39**** 0.25*** 0.43*** 1.00
GFR 0.00 0.24*** 0.14 0.16 0.28*** 0.11 0.06 −0.10 0.03 −0.31*** −0.20
N1H-C1 0.14 −0.19 −0.10 −0.18 −0.36**** −0.16 0.13 −0.01 0.14 0.02 0.18
Correlations after urine creatinine adjustment
UPCR 0.32** 0.28** 0.33*** 0.21 0.02 0.32** 0.46**** 0.44*** 0.50**** 0.55**** 1.00
GFR −0.40*** −0.11 −0.36*** −0.36*** 0.21 −0.20 −0.17 −0.19 −0.25** −0.35*** −0.20
N1H-C1 0.33** 0.10 0.31** 0.16 −0.27** 0.09 0.10 −0.05 0.16 −0.05 0.18

Values are Pearson correlation coefficients. KIM-1 kidney injury molecule-1, MCP-1 monocyte chemotactic protein-1, NGAL neutrophil gelatinase-associated lipocalin, TGFβ transforming growth factor, LFABP fatty acid-binding protein, VDBP vitamin-D binding protein, UPCR urine protein creatinine clearance

*

LFABP was only available in 36 pts

**

p < 0.05

***

p <0.005