Table 3.
Measure | NGAL | Ceruloplasmin | KIM-1 | MCP-1 | Osteopontin | TGFB | Adiponectin | Transferrin | VDBP | LFABP* | UPCR |
---|---|---|---|---|---|---|---|---|---|---|---|
Correlations of unadjusted urine concentrations | |||||||||||
NGAL | 1.00 | ||||||||||
CP | 0.29** | 1.00 | |||||||||
KIM-1 | 0.50**** | 0.25** | 1.00 | ||||||||
MCP-1 | 0 53**** | 0.50**** | 0.62**** | 1.00 | |||||||
Osteopontin | −0.13 | 0.21 | 0.13 | 0.25** | 1.00 | ||||||
TGFB | 0.53**** | 0.42*** | 0.50**** | 0.50**** | 0.22 | 1.00 | |||||
Adiponectin | 0 43*** | 0.55**** | 0.41*** | 0.45**** | 0.20 | 0.49**** | 1.00 | ||||
Transferrin | 0 40*** | 0.48**** | 0.52**** | 0.55**** | 0.15 | 0.42*** | 0.45**** | ||||
VDBP | 0.56**** | 0.44*** | 0.50**** | 0 47**** | 0.02 | 0.52**** | 0.64**** | 0.60**** | 1.00 | ||
LFABP | 0.58**** | 0.22 | 0.58**** | 0.62**** | 0.23 | 0.45**** | 0.45**** | 0.60**** | 0.74**** | 1.00 | |
UPCR | 0.30** | 0.31** | 0.30** | 0.17 | 0.00 | 0.27** | 0.45**** | 0.39*** | 0.48**** | 0.48**** | 1.00 |
GFR | −0.34*** | −0.14 | −0.38*** | −0.31** | 0.23** | −0.16 | −0.17 | −0.19 | −0.23** | −0.39**** | −0.20 |
NIH-C1 | 0.16 | −0.08 | 0.08 | −0.04 | −0.35*** | −0.06 | 0.06 | −0.07 | 0.06 | −0.09 | 0.18 |
Correlations after urine albumin adjustment | |||||||||||
UPCR | 0.03 | −0.19 | −0.23*** | −0.27*** | −0.22*** | 0.06 | 0.25*** | 0.39**** | 0.25*** | 0.43*** | 1.00 |
GFR | 0.00 | 0.24*** | 0.14 | 0.16 | 0.28*** | 0.11 | 0.06 | −0.10 | 0.03 | −0.31*** | −0.20 |
N1H-C1 | 0.14 | −0.19 | −0.10 | −0.18 | −0.36**** | −0.16 | 0.13 | −0.01 | 0.14 | 0.02 | 0.18 |
Correlations after urine creatinine adjustment | |||||||||||
UPCR | 0.32** | 0.28** | 0.33*** | 0.21 | 0.02 | 0.32** | 0.46**** | 0.44*** | 0.50**** | 0.55**** | 1.00 |
GFR | −0.40*** | −0.11 | −0.36*** | −0.36*** | 0.21 | −0.20 | −0.17 | −0.19 | −0.25** | −0.35*** | −0.20 |
N1H-C1 | 0.33** | 0.10 | 0.31** | 0.16 | −0.27** | 0.09 | 0.10 | −0.05 | 0.16 | −0.05 | 0.18 |
Values are Pearson correlation coefficients. KIM-1 kidney injury molecule-1, MCP-1 monocyte chemotactic protein-1, NGAL neutrophil gelatinase-associated lipocalin, TGFβ transforming growth factor, LFABP fatty acid-binding protein, VDBP vitamin-D binding protein, UPCR urine protein creatinine clearance
LFABP was only available in 36 pts
p < 0.05
p <0.005