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(A) Schematic representation of glyA (HP0183) inactivation in H. pylori. glyA, coding for SHMT, was partially deleted and replaced with a kanamycin resistance cassette resulting in plasmid pILL570 (glyA::aphA-3). H. pylori 26695: WT strain; HpΔglyA: glyA deletion strain. (B) Growth curves of strains H. pylori 26695 WT (black curve) and HpΔglyA (red curve) in BHI medium supplemented with 10% fetal calf serum. Each point represents the mean of three independent measurements.
