Table 2. Comparisons of baseline characteristics among UA groups according to the mean serum UA level within 1–5 years after transplantation in the 5-YR analysis.

	UA groups for 5-YR analysis
Variables	Low (n = 184)	Normal (n = 930)	High (n = 693)	P value
Transplant era				<0.001
1992–2000	71 (38.6%)	426 (45.8%)	410 (59.2%)
2001–2010	113 (61.4%)	504 (54.2%)	283 (40.8%)
Age (years)	43.9 ± 10.5†‡	40.6 ± 10.5*‡	37.7 ± 10.5*†	<0.001
Sex, male	117 (63.6%)	556 (59.8%)	484 (69.8%)	<0.001
BMI (kg/m2)	21.8 ± 3.0	21.6 ± 3.1	21.6 ± 2.9	0.72
Donor type, deceased	4 (2.2%)	66 (7.1%)	77 (11.1%)	<0.001
Donor age (years)	36.3 ± 10.0‡	37.7 ± 11.0‡	39.1 ± 12.2*†	0.005
Donor sex, male	98 (53.3%)	553 (57.3%)	388 (56.0%)	0.58
Pretransplant DM	30 (16.3%)	88 (9.5%)	19 (2.7%)	<0.001
Duration of pretransplant dialysis (months)	14.6 ± 25.0†‡	22.2 ± 35.3*	26.0 ± 39.7*	0.001
Retransplantation	10 (5.4%)	79 (8.5%)	77 (11.1%)	0.04
Number of HLA mismatches	2.4 ± 1.1	2.4 ± 1.1	2.4 ± 1.2	0.98
Tacrolimus use	71 (38.6%)	290 (31.2%)	161 (23.2%)	<0.001
Delayed graft function	0 (0%)‡	20 (2.0%)	21 (3.0%)*	0.03
BPAR within 1 year	27 (14.7%)	198 (21.3%)	227 (32.8%)	<0.001
SBP at 1 month (mmHg)	130.0 ± 14.7	130.0 ± 14.3‡	133.3 ± 14.4†	<0.001
DBP at 1 month (mmHg)	83.7 ± 10.6	83.5 ± 10.2‡	85.4 ± 10.3†	0.001
eGFR at 1 month (mL/min)	70.6 ± 18.7†‡	65.6 ± 19.7*‡	60.6 ± 20.3*†	<0.001
eGFR at 1 year (mL/min)	74.7 ± 17.1†‡	68.9 ± 16.0*‡	60.6 ± 16.0*†	<0.001
Mean serum UA between 1 and 5 year (mg/dL)	3.86 ± 0.62†‡	5.62 ± 0.77*‡	7.83 ± 1.11*†	<0.001

*P<0.05 versus the low-UA group

†P<0.05 versus the normal-UA group

‡P<0.05 versus the high-UA group in the post-hoc analysis

UA, uric acid; BMI, body mass index; DM, diabetes mellitus; HLA, human leukocyte antigen; BPAR, biopsy-proven acute rejection; SBP, systolic blood pressure; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate