Table 1. Clinical characteristics of the study population.
Study samples Patients (N = 135) |
FTD (N = 82) |
EOAD (N = 32) |
Other diagnosis* (N = 21) |
---|---|---|---|
Gender (female/male) | 48/34 | 18/14 | 9/12 |
Age at onset | 56.7±7.3 | 54 ±11.1 | 55.8±17.8 |
Dominant cases (%) | 10 (12.2%) | 12 (37.5%) | 7 (33.3%) |
Familial cases (%) | 33 (40.2%) | 9 (28.1%) | 6 (28.6%) |
Sporadic cases (%) | 30 (36.6%) | 7 (21.9%) | 5 (23.8%) |
Unknown cases (%) | 9 (11.1%) | 4 (12.5%) | 3 (14.3%) |
FTD–frontotemporal dementia (FTD group includes all subtypes of FTD); EOAD–early-onset Alzheimer’s disease.
*the ‘other diagnosis’ group includes 16 other familial/early-onset neurodegenerative/dementia disorders and 5 autosomal dominant late onset-Alzheimer’s disease (LOAD) cases.