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. 2018 Dec 14;13(12):e0208383. doi: 10.1371/journal.pone.0208383

Table 1. Clinical characteristics of the study population.

Study samples
Patients (N = 135)
FTD
(N = 82)
EOAD
(N = 32)
Other diagnosis*
(N = 21)
Gender (female/male) 48/34 18/14 9/12
Age at onset 56.7±7.3 54 ±11.1 55.8±17.8
Dominant cases (%) 10 (12.2%) 12 (37.5%) 7 (33.3%)
Familial cases (%) 33 (40.2%) 9 (28.1%) 6 (28.6%)
Sporadic cases (%) 30 (36.6%) 7 (21.9%) 5 (23.8%)
Unknown cases (%) 9 (11.1%) 4 (12.5%) 3 (14.3%)

FTD–frontotemporal dementia (FTD group includes all subtypes of FTD); EOAD–early-onset Alzheimer’s disease.

*the ‘other diagnosis’ group includes 16 other familial/early-onset neurodegenerative/dementia disorders and 5 autosomal dominant late onset-Alzheimer’s disease (LOAD) cases.