Figure 2.

Change in cortical PAC associated with stage 3 parkinsonism. The figure shows color-coded parkinsonism-associated differences in MI values during wakefulness in MC (A) and SMA (B) for monkeys A, B and C. The black boxes on the maps show the ranges of frequencies (4–10 Hz for phase and 50–150 Hz for amplitude) that were used for statistical analyses of MI differences. (C) Comparison of the sum of the differences (mean ± standard error of measurement [SEM]) between the MI values obtained in stage 3 and baseline, in the range of frequencies represented by the black box in A and B. Comparison between SMA and MC were done with Mann–Whitney tests, ^#P < 0.05, ^###P < 0.001.