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Hierarchical clustering of ROIs. Hierarchical clustering of ROIs based on their RSFC in healthy participants (top) and Parkinson patients (bottom). Using FSLNets, seeds with relatively strong RSFC were grouped first as illustrated by lower branches in the cluster trees. The qualitative comparison of both hierarchies indicates a shift of pMFC connectivity from homolog putamen to homolog M1 ROIs in Parkinson’s disease.
