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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Lung Cancer. 2018 Feb 4;117:73–79. doi: 10.1016/j.lungcan.2018.01.022

Table 2.

Associations (correlation coefficients) of G-cross scores with tumor pathologic factors

Tumor pathologic variables
G-Cross AUC Variables Tumor
histology
Tumor
differentiati on
Tumor
size
Number of
positive
lymph
nodes
Pathologic
tumor
stage
Perineural
invasion
LVSI ECE
Tumor: CD8 0.544
(P=0.91)
6.804
(P=0.10)
−0.057
(P=0.84)
−0.090
(P=0.69)
1.652
(P=1.0)
0.141
(P=0.95)
1.627
(P=0.45)
0.290
(P=0.91)
Tumor: CD68 2.826
(P=0.81)
2.608
(P=0.28)
−0.137
(P=0.49)
0.033
(P=0.89)
4.841
(P=1.0)
0.081
(P=0.95)
4.335
(P=0.25)
0.790
(P=0.91)
Tumor: CD4 0.958
(P=0.91)
1.421
(P=0.45)
−0.051
(P=0.86)
0.008
(P=0.95)
1.795
(P=1.0)
1.077
(P=0.95)
0.370
(P=0.76)
1.104
(P=0.91)
Tumor: FoxP3 2.239
(P=0.88)
2.486
(P=0.28)
0.027
(P=0.92)
−0.086
(P=0.69)
8.219
(P=0.67)
0.014
(P=0.97)
0.177
(P=0.76)
0.122
(P=0.91)
Tumor: CD8 + CD68 2.283
(P=0.88)
4.776
(P=0.16)
−0.066
(P=0.82)
−0.007
(P=0.95)
2.727
(P=1.0)
0.190
(P=0.95)
7.005
(P=0.07)
2.116
(P=0.89)
Tumor: CD8 + CD4 0.863
(P=0.91)
5.900
(P=0.10)
−0.046
(P=0.86)
−0.036
(P=0.89)
2.017
(P=1.0)
0.418
(P=0.95)
2.461
(P=0.39)
0.132
(P=0.91)
Tumor: CD8 + FoxP3 0.827
(P=0.91)
6.409
(P=0.10)
−0.033
(P=0.92)
−0.086
(P=0.69)
1.425
(P=1.0)
0.032
(P=0.96)
1.517
(P=0.45)
0.197
(P=0.91)
Tumor: CD68 + CD4 1.303
(P=0.91)
2.191
(P=0.31)
−0.094
(P=0.71)
0.043
(P=0.90)
3.284
(P=1.0)
0.684
(P=0.95)
2.893
(P=0.37)
0.040
(P=0.91)
Tumor: CD68 + FoxP3 1.116
(P=0.91)
4.206
(P=0.18)
−0.081
(P=0.74)
0.009
(P=0.95)
3.020
(P=1.0)
0.044
(P=0.96)
3.386
(P=0.35)
0.675
(P=0.91)
Tumor: CD4 + Foxp3 1.815
(P=0.91)
3.407
(P=0.22)
−0.018
(P=0.92)
−0.011
(P=0.95)
2.509
(P=1.0)
0.380
(P=0.95)
0.270
(P=0.76)
0.490
(P=0.91)
FoxP3: CD8 11.396
(P=0.09)
0.0003
(P=1.0)
0.140
(P=0.49)
−0.041
(P=0.90)
10.700
(P=0.33)
0.190
(P=0.95)
0.286
(P=0.76)
0.197
(P=0.91)
*

None of the above correlations reached statistical significance, adjusted P < 0.05.

Abbreviations: KPS = Karnofsky performance status, LVSI = lymphovascular space invasion.