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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Lung Cancer. 2018 Feb 4;117:73–79. doi: 10.1016/j.lungcan.2018.01.022

Table 3.

Univariate Cox regression of clinicopathologic and treatment factors associated with overall survival

Characteristic HR 95% CI P value
Age 1.04 1.02–1.07 0.0007
Gender 1.26 0.78–2.0 0.34
KPS 1.003 0.98–1.03 0.81
Positive smoking history 1.002 0.99–1.01 0.70
Pathologic tumor stage
 I
 II
 III		 1
1.65
1.13		 -
0.46–5.88
0.36–3.64		 -
0.44
0.83
Tumor histology
 Adenocarcinoma
 Squamous
 NSCLC, NOS
 Sarcomatoid		 1
0.9
0.86
0.64		 -
0.53–1.52
0.4–1.84
0.09–4.73		 -
0.68
0.70
0.67
Tumor differentiation
 Well
 Moderate
 Poor		 1
0.55
0.36		 -
0.27–1.12
0.18–0.75		 -
0.10
0.006
Number of positive lymph nodes 1.13 1.05–1.21 0.0014
Perineural invasion 1.85 0.67–5.11 0.24
LVSI 0.89 0.51–1.53 0.67
ECE 1.10 0.50–2.42 0.81
Adjuvant chemotherapy treatment 0.72 0.46–1.15 0.17

Boldface type indicates statistical significance on univariate analysis.

Abbreviations: KPS = Karnofsky performance status, LVSI = Lymphovascular space invasion, ECE = Extracapsular extension, HR = hazard ratio, CI = confidence interval.