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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Lung Cancer. 2018 Feb 4;117:73–79. doi: 10.1016/j.lungcan.2018.01.022

Table 4.

Multivariate Cox regression of G-cross AUC scores and clinical factors with overall survival

Characteristic HR 95% CI P value
Age 1.04 1.01–1.06 0.002
Number of positive lymph nodes 1.18 1.08–1.29 0.0002
Tumor: CD8 (G-cross) 0.96 0.87–1.06 0.42
Tumor: CD68 (G-cross) 0.91 0.78–1.06 0.24
Tumor: CD4 (G-cross) 0.96 0.83–1.12 0.60
Tumor: FoxP3 (G-cross) 1.52 1.11–2.07 0.009
CD8: FoxP3 (G-cross) 0.96 0.92–0.99 0.042
Tumor: CD8+CD68 (G-cross) 0.95 0.88–1.03 0.23
Tumor: CD8+CD4 (G-cross) 0.97 0.89–1.05 0.40
Tumor: CD8+FoxP3 (G-cross) 0.99 0.90–1.08 0.77
Tumor: CD4+CD68 (G-cross) 0.95 0.86–1.05 0.33
Tumor: FoxP3+CD68 (G-cross) 0.98 0.86–1.11 0.71
Tumor: FoxP3+CD4 (G-cross) 0.99 0.90–1.15 0.81

Boldface type indicates statistical significance on multivariate analysis.

Abbreviations: AUC = area under the curve, HR = hazard ratio, CI = confidence interval.