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. 2018 Oct 10;46(22):11789–11805. doi: 10.1093/nar/gky928

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© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — R-loop accumulation is the mirror of nucleosome accumulation and is dictated by RNaseH1 throughout RNA Pol II transcription units. (A) Metaplots of WT (pink) and Tbrh1–/– (green) DRIP signal over the ATG (±500 bp) of the first gene of each Pol II PTU (left) and over all other genes in the PTU (right). (B) Metaplot analysis of DRIP (blue) and histone H3 ChIP (red) signal over the ATG (±500 bp) of the first gene of each Pol II PTU (left) and all other Pol II transcibed genes (right).