Table 1.
SDOS interacting proteins obtained by label-free quantitative proteomics
| Gene names | Protein names | Significance (log10 t-test P-value) | Difference (SDOS/eGFP log2 FC) |
|---|---|---|---|
| TP53BP1 | Tumor suppressor p53-binding protein 1 | 8.25077 | 11.0722 |
| CCT5 | T-complex protein 1 subunit epsilon | 7.1619 | 5.88357 |
| DYNLL1; DYNLL2 | Dynein light chain 1, cytoplasmic;Dynein light chain 2, cytoplasmic | 5.98194 | 7.46163 |
| SLC7A5 | Large neutral amino acids transporter small subunit 1 | 5.66293 | 6.46204 |
| CCT4 | T-complex protein 1 subunit delta | 5.64192 | 7.6541 |
| SLC16A3 | Monocarboxylate transporter 4 | 5.59991 | 4.88154 |
| TUBA4A | Tubulin alpha-4A chain | 4.91233 | 4.91643 |
| TUBB8 | Tubulin beta-8 chain | 3.99008 | 9.00189 |
| TUBA1A; TUBA3C; TUBA3E | Tubulin alpha-1A chain;Tubulin alpha-3C/D chain;Tubulin alpha-3E chain | 3.72152 | 7.84447 |
| PPP6C | Serine/threonine-protein phosphatase 6 catalytic subunit | 3.70021 | 3.92096 |
| POLDIP2 | Polymerase delta-interacting protein 2 | 3.53627 | 4.22019 |
| SQSTM1 | Sequestosome-1 | 3.4972 | 7.90479 |
| ANKRD28 | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A | 3.46259 | 4.00495 |
| MIF | Macrophage migration inhibitory factor | 3.43102 | 5.75599 |
| BAG2 | BAG family molecular chaperone regulator 2 | 3.30518 | 6.02968 |
| PPP6R3 | Serine/threonine-protein phosphatase 6 regulatory subunit 3 | 3.30512 | 4.82287 |
| LGALS3BP | Galectin-3-binding protein | 3.08069 | 9.86244 |
| TRAP1 | Heat shock protein 75 kDa, mitochondrial | 3.035 | 6.92604 |
| TCEAL1 | Transcription elongation factor A protein-like 1 | 2.82362 | 6.00085 |
| HNRNPH3 | Heterogeneous nuclear ribonucleoprotein H3 | 2.67817 | 6.1067 |
| NUDT16 | U8 snoRNA-decapping enzyme | 2.61619 | 8.05465 |
| RPS28 | 40S ribosomal protein S28 | 2.3294 | 4.91507 |
| CCT8 | T-complex protein 1 subunit theta | 2.25142 | 6.83071 |
| SLC25A10 | Mitochondrial dicarboxylate carrier | 2.20143 | 5.34728 |
| USP11 | Ubiquitin carboxyl-terminal hydrolase 11 | 2.17424 | 7.29486 |
| LAMA1 | Laminin subunit alpha-1 | 2.10802 | 4.40167 |
| SLC25A6; SLC25A4 | ADP/ATP translocase 3;ADP/ATP translocase 1 | 1.98901 | 5.70873 |
| HDAC6 | Histone deacetylase 6 | 1.84778 | 3.31599 |
| SBSN | Suprabasin | 1.82849 | 4.65037 |
| CPS1 | Carbamoyl-phosphate synthase [ammonia], mitochondrial | 1.64454 | 5.035 |
| CCT2 | T-complex protein 1 subunit beta | 1.63926 | 4.41436 |
| CCT7 | T-complex protein 1 subunit eta | 1.54531 | 5.05293 |
| S100A7; S100A7A | Protein S100-A7;Protein S100-A7A | 1.53909 | 5.10047 |
| HAGH | Hydroxyacylglutathione hydrolase, mitochondrial | 1.39384 | 2.8948 |
| HSPA8 | Heat shock cognate 71 kDa protein | 1.37934 | 6.06043 |
| TOMM40 | Mitochondrial import receptor subunit TOM40 homolog | 1.32786 | 3.5971 |
| SNRPA1 | U2 small nuclear ribonucleoprotein A | 1.30897 | 5.05506 |
| HSPA5 | 78 kDa glucose-regulated protein | 1.30267 | 5.11503 |