Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Oct 24;46(22):12166–12176. doi: 10.1093/nar/gky970

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 6. — Structural difference between TREX2 and other DEDDh exonucleases in DNA binding. (A) Structural comparison of mTREX2-Y-shaped DNA complex and TREX1-dI-T–dsDNA complex. The DNA and protein of TREX1-dI-T–dsDNA complex are colored gray. (B–F) Schematic diagram of TREX2 and other DEDDh exonucleases in complex with duplex DNA/RNA. The active sites in these structures are displayed as orange circles. The lower panel shows the protein–DNA interacting pattern of various DEDDh exonuclease–DNA complexes. The interaction between protein and DNA are marked by black balls. SAP in (F) is the SAP domain in 3′hExo.