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This article is published online with Open Access and distributed under the terms of the Creative Commons Attribution Non-Commercial License (CC BY-NC 4.0).
Sequence identity of all murine germline CDRH1 and CDRH2 to the closest human germline CDRs (A) and correlation of the number of mutations in FR (black) and CDR (grey) regions of recommended humanized mAbs (list 77; 2017) with germinality of the closest related human germline V genes (B).