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. 2018 Dec 14;38(6):BSR20181386. doi: 10.1042/BSR20181386

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© 2018 The Author(s).

This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY).

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(A) and (B) miR-133a knockdown increased the mRNA and protein expression of SOX4 in ABHD11-AS1 knockdown. (C) Quantify the signal intensity of Western blots. (D) and (E) CellTiter-Glo assays showed that miR-133a could largely reverse the suppressive effects of ABHD11-AS1 knockdown on proliferation. (F) miR-133a silencing partly rescued the colony formation of CRC cells after ABHD11-AS1 knockdown. (G) Down-regulation of miR-133a largely decreased the promotion of apoptosis in CRC cells transfected with si-ABHD11-AS1. (H) and (I) miR-133a silencing partly reversed the suppressive effects of ABHD11-AS1 on migration and invasion. *P < 0.05, **P < 0.01.