Table 2. Meta-analysis of ICAM1 rs5498 and multiple sclerosis risk.
| Genetic model | Sample size | Association analysis | Heterogeneity assessment | |||
|---|---|---|---|---|---|---|
| Study | Case/control | Passociation | OR (95% CI) | Pheterogeneity | I2 | |
| Allelic G vs A | 11 | 1786/2137 | 0.036 | 0.91 [0.83–0.99] | 0.051 | 45.1% |
| GG vs AA | 10 | 1436/1639 | 0.070 | 0.83 [0.68–1.02] | 0.104 | 38.1% |
| AG vs AA | 10 | 1436/1639 | 0.086 | 0.86 [0.73–1.02] | 0.147 | 32.6% |
| AG+GG vs AA | 10 | 1436/1639 | 0.042 | 0.85 [0.73–0.99] | 0.070 | 43.2% |
| GG vs AA+AG | 10 | 1436/1639 | 0.416 | 0.93 [0.78–1.11] | 0.173 | 29.5% |
| Carrier G vs A | 10 | 1436/1639 | 0.287 | 0.94 [0.83–1.06] | 0.660 | 0.0% |
Abbreviations: CI, 95% confidence interval; OR, odds ratio.