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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Int J Cancer. 2018 Oct 26;144(3):582–594. doi: 10.1002/ijc.31908

FIGURE 6. Necessity of CINP for KLF5-mediated gene regulation and a model for the dependency of KLF5 on CINP to promote tumor growth.

FIGURE 6.

(A-D) Silencing CINP attenuated the function of KLF5 in gene regulation, as detected by both real-time qPCR (A, B) and western blotting (C, D) in both TSU-Pr1 cells (A, C) and HeLa cells (B, D). (E, F) Expression of cyclin D1 and caspase 7 was measured by IHC in TSU-Pr1 xenografts. (G) A model for KLF5-CINP interaction in KLF5-promoted tumor growth. n.s., not significant; *, P<0.5; **, P<0.01; ***, P<0.001.