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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Am Heart J. 2018 Oct 2;206:51–60. doi: 10.1016/j.ahj.2018.09.014

Table III.

Comparison of men versus women (reference = women at each level of CAD) of 5-year mortality at each level of CAD severity

CAD severity Unadjusted model Adjusted model*
HR for M vs F (95% CI) P value HR for M vs F (95% CI) P value
Overall, stratified by CAD severity 1.03 (0.96–1.10) .4951 1.29 (1.20–1.40) <.0001
No CAD 1.35 (1.15–1.59) .0002 1.56 (1.32–1.85) <.0001
Nonobstructive 1.20 (1.04–1.38) .0113 1.43 (1.23–1.65) <.0001
Obstructive 0.87 (0.79–0.95) .0030 1.16 (1.05–1.28) .0020
*

Adjusted model includes the following covariates: age, race, BMI, prior MI, diabetes, hypertension, hyperlipidemia, peripheral vascular disease, congestive heart failure, chronic obstructive pulmonary disease, renal disease, smoking history, noncardiac Charlson comorbidity index >1, and year of cath. Interaction between CAD severity and sex was significant in both the unadjusted and adjusted models (interaction P < .01 for both).

Overall sex HRs are estimated by fitting the unadjusted Cox model stratified by CAD severity and the adjusted Cox model stratified by CAD severity.