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. 2018 Dec 14;8:17878. doi: 10.1038/s41598-018-36226-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Genetic variability in human and chicken Toll-like receptors (TLRs) and hypervariable segment I (HVS-I) of the mitochondrial DNA. (a) Comparison of numbers of single nucleotide variants (SNVs; left axis) and nucleotide diversity (right axis; red) found in human (h; blue) and chicken (ch; yellow) TLRs and HVS-I. Synonymous variants are shown in light colours and non-synonymous variants in dark colours. (b) Comparison of numbers of alleles and protein variants of TLRs found in human (h; blue) and chicken (ch; yellow) populations and number of alleles found in HVS-I. Total numbers of TLR protein variants are highlighted in dark colours, while numbers of alleles are represented by the total height of each bar (combination of light and dark colours). Numbers above the bars and points indicate the fold differences between values for humans and chickens. Error bars denote standard deviations (in TLR genes the bars are too short to be visible).