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. 2018 Dec 14;8:17878. doi: 10.1038/s41598-018-36226-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of minor variant frequencies in human and chicken TLR single nucleotide variants (SNVs). Human TLRs (hTLRs) are highlighted in blue and chicken TLRs (chTLRs) in yellow, while allele frequencies of equivalent TLRs are shown specularly. Synonymous variants are shown in light colours and non-synonymous variants in dark colours. The left axis shows number of SNVs, while the right axis indicates the proportion of SNVs on a relative scale.