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. 2018 Dec 14;3:33. doi: 10.1038/s41525-018-0073-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — CNV reported in CP to date. Circos plot generated using the ClicO FS tool shows the human karyogram on the outer edge with deletions in red and duplications in blue from this study and the previous four reports as indicated by the study key. The saturation of colour of each CNV indicates its likelihood for pathogenicity