Table 3.

Transporter, 5-HT_1A and 5-HT_2A binding in suicide and major depressive disorder

All cases were sudden-death cases.
Receptor	n	Group	BA 8	BA 9	BA 46	BA 45	BA 47	BA 11	BA 12	BA 32	BA 24
SERT	143	NonSuicide	5.86 ± 2.13	6.38 ± 2.6	6.83 ± 2.84	8.81 ± 4.42	9.62 ± 5.22	10.13 ± 5.55	11.21 ± 5.36	9.9 ± 4.29	23.91 ± 11.98
	77	Suicide	5.35 ± 2.61	5.76 ± 2.96	5.81 ± 3.46*	7.65 ± 4.31	8.8 ± 5.43	9.52 ± 6.15*	9.34 ± 5.5*	9.05 ± 6.53	20.49 ± 16.63
5-HT1A	143	NonSuicide	13.93 ± 4.77	14.66 ± 4.99	14.24 ± 4.79	14.75 ± 4.64	17.72 ± 5.57	19.18 ± 6.54	18.42 ± 6.2	16.15 ± 5.55	19.45 ± 7.18
	79	Suicide	14.19 ± 4.03	14.59 ± 4.64	14.97 ± 4.61*	15.19 ± 3.86	18.07 ± 4.87	19.68 ± 5.97	18.62 ± 5.43	16.26 ± 3.97	18.49 ± 6.08
5-HT2A	145	NonSuicide	29.38 ± 10.82	29.58 ± 10.82	29.36 ± 9.96	30.36 ± 10.55	32.76 ± 11.35	33.13 ± 11.55	33.22 ± 11.52	30.03 ± 10.05	25.48 ± 9.57
	78	Suicide	30.05 ± 12.09	30.34 ± 12.54	31.41 ± 12.59	30.24 ± 11.48	33.65 ± 12.52	33.43 ± 12.55	32.93 ± 12.5	30 ± 11.69	23.21 ± 9.05

Only cases with psychological autopsy:
Receptor	n	Group	BA 8	BA 9	BA 46	BA 45	BA 47	BA 11	BA 12	BA 32	BA 24
SERT	102	NonSuicide	5.7 ± 2.1	6.3 ± 2.58	6.73 ± 2.73	8.46 ± 4.53	9 ± 5.06	9.55 ± 4.79	10.92 ± 4.95	9.58 ± 4.17	22.54 ± 11.58
	55	Suicide	4.58 ± 2.19	5.33 ± 2.64	5.4 ± 3.07	6.8 ± 3.64	8.11 ± 5.42	8.9 ± 6.5	8.15 ± 4.76	7.61 ± 4.55	15.63 ± 12.95
5-HT1A	100	NonSuicide	12.79 ± 3.76	14.01 ± 4.34	13.28 ± 3.84	14.06 ± 4.28	16.51 ± 5.32	17.98 ± 5.85	17.42 ± 5.95	14.81 ± 5.04	18.14 ± 6.43
	56	Suicide	14.68 ± 4.06*	14.88 ± 4.4	15.53 ± 4.34*	15.26 ± 3.55	18.27 ± 4.85*	20.06 ± 5.8*	18.8 ± 4.86	16.09 ± 4.16	19.67 ± 5.96
5-HT2A	104	NonSuicide	27.37 ± 9.08	28.42 ± 10.37	29.14 ± 9.88	29.65 ± 10.12	32.1 ± 10.57	32.99 ± 11.3	32.96 ± 11.22	29.35 ± 9.34	24.6 ± 8.74
	56	Suicide	31.09 ± 13.85*	31.67 ± 13.68*	32.82 ± 13.26*	31.76 ± 12.19	35.41 ± 13.15*	35.43 ± 13.03	34.31 ± 13.42	31.07 ± 12.92	23.43 ± 9.82
SERT	112	NoMDD	5.65 ± 2.11	6.33 ± 2.62	6.65 ± 2.71	8.41 ± 4.49	9.11 ± 5.27	9.77 ± 5.24	10.85 ± 4.97	9.63 ± 4.21	21.83 ± 12.17
	47	MDD	4.55 ± 2.17	5.1 ± 2.45*	5.28 ± 3.14*	6.6 ± 3.44*	7.68 ± 4.81	8.2 ± 5.71	7.72 ± 4.52*	7.04 ± 4.27*	16.28 ± 11.94
5-HT1A	110	NoMDD	13 ± 3.63	14.14 ± 4.22	13.68 ± 3.93	14.31 ± 4.09	16.92 ± 5.03	18.54 ± 5.6	17.67 ± 5.81	15.04 ± 4.79	18.19 ± 6.07
	48	MDD	14.72 ± 4.49*	14.94 ± 4.7	15.15 ± 4.47*	14.99 ± 3.93	17.71 ± 5.48	19.16 ± 6.52	18.61 ± 4.99	15.96 ± 4.67	19.77 ± 6.77*
5-HT2A	112	NoMDD	28.03 ± 10.31	29.02 ± 11.12	29.7 ± 10.63	29.97 ± 10.4	32.79 ± 11.24	33.53 ± 11.67	33.28 ± 11.84	29.63 ± 9.83	24.91 ± 9.03
	50	MDD	29.72 ± 12.27	30.8 ± 12.85	32.22 ± 12.57	31.35 ± 11.78	34.18 ± 12.23	34.19 ± 12.66	33.55 ± 12.34	30.61 ± 12.31	21.6 ± 8.39

Values are expressed as fmol/mg tissue, mean ± SD

*p < 0.05