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. 2018 Dec 14;8:279. doi: 10.1038/s41398-018-0309-1

Table 5.

Transporter, 5-HT1A and 5-HT2A binding in suicide and early life adversity

Receptor n Group BA 8 BA 9 BA 46 BA 45 BA 47 BA 11 BA 12 BA 32 BA 24
SERT 67 Nonsuicide, No ELA 5.3 ± 2.17 6.03 ± 2.67 6.26 ± 2.53 8.07 ± 4.99 8.63 ± 5.68 8.93 ± 4.85 10.15 ± 4.04 9.3 ± 4.63 19.94 ± 10.87
31 Suicide, No ELA 4.73 ± 2.33 5.06 ± 2.7 4.85 ± 2.76 6.4 ± 3.7 7.93 ± 6.55 8.88 ± 7.97 7.39 ± 4.67 7.48 ± 5.19 11.45 ± 10.04
31 Nonsuicide, ELA 6.38 ± 1.87 6.76 ± 2.28 7.69 ± 2.85 9.26 ± 3.2 9.63 ± 3.45 10.52 ± 4.26 12.62 ± 6.15 10.1 ± 3.2 27.17 ± 11.65
19 Suicide, ELA 3.91 ± 1.71 5.59 ± 2.54 5.93 ± 3.27 7.03 ± 3.21 8.07 ± 3.66 8.88 ± 4.51 8.81 ± 4.76a 8.19 ± 3.86 19.96 ± 16.71
5-HT1A 67 Nonsuicide, No ELA 12.68 ± 3.81 13.47 ± 4.15 12.69 ± 3.77 13.47 ± 4.09 15.3 ± 4.87 16.48 ± 5.24 16.28 ± 5.96 14.08 ± 4.84 17.3 ± 6.62
31 Suicide, No ELA 14.5 ± 3.85 14.7 ± 4.98 14.81 ± 5.06 15.01 ± 3.97 18.52 ± 5.12 20.59 ± 6.44 19.04 ± 5.23 15.93 ± 4.76 19.69 ± 6.11
30 Nonsuicide, ELA 12.64 ± 3.58 14.98 ± 4.64 14.45 ± 3.83 15.22 ± 4.51 18.33 ± 4.68 20.36 ± 5.3 19.51 ± 5.21 16.14 ± 5.19 19.1 ± 5.45
20 Suicide, ELA 14.18 ± 2.95 14.86 ± 3.79 15.94 ± 3.02 15.19 ± 3.08 17.46 ± 4.38 19.04 ± 4.92 17.88 ± 4.25 15.64 ± 2.71 18.21 ± 5.83
5-HT2A 69 Nonsuicide, No ELA 27.74 ± 8.84 28.15 ± 10.11 28.49 ± 9.71 29.72 ± 10.34 31.79 ± 10.76 32.94 ± 11.31 32.43 ± 11.01 29.39 ± 8.77 25.74 ± 8.63
31 Suicide, No ELA 25.51 ± 11.68 27.07 ± 12.35 28.65 ± 12.75 27.07 ± 11.59 30.7 ± 12.58 31.16 ± 13.51 29.08 ± 11.61 26.08 ± 11.73 19.49 ± 8.54
31 Nonsuicide, ELA 27.47 ± 9.92 29.5 ± 11.05 30.58 ± 10.54 30.19 ± 10.15 33.77 ± 10.01 34.03 ± 11.3 33.81 ± 11.94 30.13 ± 10.45 22.37 ± 8.89
20 Suicide, ELA 37.18 ± 12.78 37.89 ± 12.89 37.01 ± 12.5 37.05 ± 10.66 41.2 ± 12.07 40.73 ± 10.35 39.34 ± 12.73 35.76 ± 11.89 29.21 ± 10.45

Values are expressed as fmol/mg tissue, mean ± SD

BA Brodmann area, ELA early live adversity, SERT serotonin transporter