Table 2.

Clinical stability

	Morphine	Placebo	Median difference (95% CI)	p value
6 h
Oxygen desaturation	0·57 (0·00 to 0·99)	−0·06 (−0·65 to 0·00)	0·66 (0·36 to 1·00)	0·0007
Bradycardia	0·50 (0·00 to 0·99)	0·00 (0·00 to 0·98)	0·33 (0·00 to 0·98)	0·07
Tachycardia	0·00 (0·00 to 0·00)	0·00 (0·00 to 0·00)	0·00 (−0·16 to 0·00)	0·32
24 h
Oxygen desaturation	0·22 (−0·02 to 0·98)	0·00 (−0·25 to 0·08)	0·33 (0·03 to 0·75)	0·019
Bradycardia	0·43 (0·00 to 1·00)	0·00 (−0·50 to 0·60)	0·43 (0·00 to 1·00)	0·019
Tachycardia	0·00 (−0·50 to 0·98)	0·00 (0·00 to 0·00)	0·00 (−0·38 to 0·98)	0·57

Data are median (IQR) of the standardised difference in number of episodes before and after intervention, unless otherwise stated.