Fig. 1.

Full-fusion events are the most common. (A) Recording from a wild-type IHC that shows a staircase of up steps in C_m (black trace), which appear to lack correlated changes in conductance (red trace) or membrane current (green trace). (a1–a3) Magnified view of fusion events from A (individual steps a1–a3 presented at same scale as in a1). (B) Same traces as in A (C_m and G), but not smoothed to reveal potential transient G signals associated with C_m fusion events. Lock-in sinewave settings: frequency, 58.5 kHz; V_rms, 200 mV.