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. 2018 Nov 21;115(50):12811–12816. doi: 10.1073/pnas.1811814115

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Copyright © 2018 the Author(s). Published by PNAS.

This open access article is distributed under Creative Commons Attribution License 4.0 (CC BY).

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Fig. 4. — Fusion event amplitudes fall within the range of SVs common to IHCs. (A) Fusion events from a wild-type (wt) cell are aligned to their rising phase (average: thick red line). (B) Fusion event amplitude distribution for the patch in A. (C) Full range of wild-type event amplitudes. (D) Zoomed view of C. (E) Transformation of wild-type event amplitudes into full range of equivalent vesicle diameters (solid line is the Gaussian fit to equivalent diameter data; dashed line is SV diameter from EM; ref. 33). (F) Plots the full range of calculated vesicle volumes. (G) Full range of fusion event amplitudes recorded from Cav1.3 ko IHCs. (H) Zoomed view of G.